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Gene transcription by RNA polymerase II is a fundamental process in eukaryotic cells. The precise regulation of transcription is necessary for cellular growth and development and requires the coordinated activ...
Extracellular vesicles (EVs) are amongst the most promising candidates for developing blood-based biomarkers. However, patient sample availability is a key barrier to translational research whilst most biobank...
Primary tumour biology and axillary lymph node status are key prognostic factors in breast cancer treatment. The LowMag trial introduced a magnetic sentinel lymph node biopsy procedure using a superparamagneti...
Functional evaluation of molecules that are predicted to promote stem cell mediated endogenous repair often requires in vivo transplant studies that are low throughput and hinder the rate of discovery. To offe...
Recent technological advancements have vastly improved access to high-throughput biological instrumentation, sparking an unparalleled surge in omics data generation. The implementation of artificial intelligen...
Genome editing enables precise genetic manipulation in plants, offering hope for tackling global food insecurity and malnutrition by enhancing crop traits and nutritional content. The BMC Methods Collection ‘Geno...
Methods in tissue engineering and regenerative medicine are constantly evolving to address the complex challenges of repairing damaged tissues and modeling diseased organs using a library of various biomateria...
In the ever-evolving landscape of scientific research, the importance of detailed, accessible methods and step-by-step reusable protocols cannot be overstated. In alignment with this BMC Methods, is dedicated ...